Molecular fixative enables expression microarray analysis of microdissected clinical cervical specimens
نویسندگان
چکیده
منابع مشابه
Molecular fixative enables expression microarray analysis of microdissected clinical cervical specimens.
Formalin-fixed tissue has been a mainstay of clinical pathology laboratories, but formalin alters many biomolecules, including nucleic acids and proteins. Meanwhile, frozen tissues contain better-preserved biomolecules, but tissue morphology is affected, limiting their diagnostic utility. Molecular fixatives promise to bridge this gap by simultaneously preserving morphology and biomolecules, en...
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Nosocomial infections caused by Staphylococcus aureus are clinically serious and control of such infections requires strain typing to identify the source of contamination. Recently, pulsed-field gel electrophoresis (PFGE) and random amplified polymorphic DNA (RAPD) assay have been introduced and have provided a high level of strain discrimination of S. aureus isolated from clinical specimens. T...
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ژورنال
عنوان ژورنال: Experimental and Molecular Pathology
سال: 2014
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2013.12.007